Biotechnological Transformation of Hydrocortisone into 16α-Hydroxyprednisolone by Coupling <i>Arthrobacter simplex</i> and <i>Streptomyces roseochromogenes</i>

Biotechnological Transformation of Hydrocortisone into 16α-Hydroxyprednisolone by Coupling <i>Arthrobacter simplex</i> and <i>Streptomyces roseochromogenes</i>

16α-Hydroxyprednisolone, an anti-inflammatory drug, could be potentially obtained from hydrocortisone bioconversion by combining a 1,2-dehydrogenation reaction performed by <i>Arthrobacter simplex</i><i>ATCC</i>31652 with a 16α-hydroxylation reaction by <i>Streptomyces...

Full description

Bibliographic Details
Main Authors: Odile Francesca Restaino, Simona Barbuto Ferraiuolo, Addolorata Perna, Marcella Cammarota, Maria Giovanna Borzacchiello, Antonio Fiorentino, Chiara Schiraldi
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
<i>Arthrobacter simplex</i>
bioconversion
hydrocortisone
16α-hydroxyhydrocortisone
16α-hydroxyprednisolone
prednisolone
Online Access:https://www.mdpi.com/1420-3049/25/21/4912

Internet

https://www.mdpi.com/1420-3049/25/21/4912

Similar Items