Differential regulation of TGF-β/Smad signaling in hepatic stallate cells between acute and chronic liver injuries
Current evidence suggests that regulation of extracellular matrix (ECM) accumulation by fibrogenic TGF-β and PDGF signals involves different mechanisms in acute and chronic liver injuries, even though hepatic stellate cells (HSC) are the principal effecter in both cases. As a result of chronic liver...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012-03-01
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| Series: | Frontiers in Physiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00053/full |