LPSlow-Macrophages Alleviate the Outcome of Graft-Versus-Host Disease Without Aggravating Lymphoma Growth in Mice

LPSlow-Macrophages Alleviate the Outcome of Graft-Versus-Host Disease Without Aggravating Lymphoma Growth in Mice

Despite significant therapeutic advances, graft-versus-host disease (GvHD) remains the main life-threatening complication following allogeneic hematopoietic stem cell transplantation. The pathogenesis of GvHD is dominated by a dysregulated allogeneic immune response that drives fibrosis and autoimmu...

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Bibliographic Details
Main Authors: Mohamed Jeljeli, Charlotte Chêne, Sandrine Chouzenoux, Marine Thomas, Benjamin Segain, Ludivine Doridot, Carole Nicco, Frédéric Batteux
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
macrophages
trained immunity
graft-versus-host disease
alloimmunity
inflammation
anti-tumoral action
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.670776/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.670776/full

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