Stability and ocular biodistribution of topically administered PLGA nanoparticles

Abstract Polymeric nanoparticles have been investigated as potential delivery systems for therapeutic compounds to address many ailments including eye disease. The stability and spatiotemporal distribution of polymeric nanoparticles in the eye are important regarding the practical applicability and...

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Bibliographic Details
Main Authors: Sean Swetledge, Renee Carter, Rhett Stout, Carlos E. Astete, Jangwook P. Jung, Cristina M. Sabliov
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90792-5