The Relation Between Brain Amyloid Deposition, Cortical Atrophy, and Plasma Biomarkers in Amnesic Mild Cognitive Impairment and Alzheimer’s Disease

The Relation Between Brain Amyloid Deposition, Cortical Atrophy, and Plasma Biomarkers in Amnesic Mild Cognitive Impairment and Alzheimer’s Disease

Background: Neuritic plaques and neurofibrillary tangles are the pathological hallmarks of Alzheimer’s disease (AD), while the role of brain amyloid deposition in the clinical manifestation or brain atrophy remains unresolved. We aimed to explore the relation between brain amyloid deposition, cortic...

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Bibliographic Details
Main Authors: Ling-Yun Fan, Kai-Yuan Tzen, Ya-Fang Chen, Ta-Fu Chen, Ya-Mei Lai, Ruoh-Fang Yen, Ya-Yao Huang, Chyng-Yann Shiue, Shieh-Yueh Yang, Ming-Jang Chiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
plasma Aβ40
plasma tau
beta-amyloid
amyloid PET
cortical thickness
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00175/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2018.00175/full

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