The Relationships between Polymorphisms in Genes Encoding the Growth Factors TGF-β1, PDGFB, EGF, bFGF and VEGF-A and the Restenosis Process in Patients with Stable Coronary Artery Disease Treated with Bare Metal Stent.

The Relationships between Polymorphisms in Genes Encoding the Growth Factors TGF-β1, PDGFB, EGF, bFGF and VEGF-A and the Restenosis Process in Patients with Stable Coronary Artery Disease Treated with Bare Metal Stent.

BACKGROUND:Neointima forming after stent implantation consists of vascular smooth muscle cells (VSMCs) in 90%. Growth factors TGF-β1, PDGFB, EGF, bFGF and VEGF-A play an important role in VSMC proliferation and migration to the tunica intima after arterial wall injury. The aim of this paper was an a...

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Bibliographic Details
Main Authors: Tadeusz Osadnik, Joanna Katarzyna Strzelczyk, Rafał Reguła, Kamil Bujak, Martyna Fronczek, Małgorzata Gonera, Marcin Gawlita, Jarosław Wasilewski, Andrzej Lekston, Anna Kurek, Marek Gierlotka, Przemysław Trzeciak, Michał Hawranek, Zofia Ostrowska, Andrzej Wiczkowski, Lech Poloński, Mariusz Gąsior
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4773170?pdf=render

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http://europepmc.org/articles/PMC4773170?pdf=render

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