Spatiotemporal and functional characterisation of the Plasmodium falciparum cGMP-dependent protein kinase.

Signalling by 3'-5'-cyclic guanosine monophosphate (cGMP) exists in virtually all eukaryotes. In the apicomplexan parasite Plasmodium, the cGMP-dependent protein kinase (PKG) has previously been reported to play a critical role in four key stages of the life cycle. The Plasmodium falciparu...

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Bibliographic Details
Main Authors: Christine S Hopp, Christian Flueck, Lev Solyakov, Andrew Tobin, David A Baker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3489689?pdf=render