Construction of a recombinant eukaryotic expression vector containing PHD3 gene and its expression in HepG2 cells

<p>Abstract</p> <p>Prolyl hydroxylase domain 3 (PHD3) is a hypoxia inducible factor-α (HIFα) regulator; it degrades HIFα in the presence of oxygen. Recently, there have been an increasing number of studies about the role of PHD3 in proliferation and apoptosis of cancer cells. Howev...

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Bibliographic Details
Main Authors: Liang Qi-Lian, Li Zhou-Yu, Zhou Yuan, Liu Qiu-Long, Ou Wen-Ting, Huang Zhi-Gang
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://www.jeccr.com/content/31/1/64