Phase II Randomized Study of Plitidepsin (Aplidin), Alone or in Association with L-carnitine, in Patients with Unresectable Advanced Renal Cell Carcinoma

Phase II Randomized Study of Plitidepsin (Aplidin), Alone or in Association with L-carnitine, in Patients with Unresectable Advanced Renal Cell Carcinoma

This randomized phase II study evaluated two schedules of the marine compound Plitidepsin with or without co-administration of L-carnitine in patients with renal cell carcinoma. Patients had adequate performance status and organ function.The primary endpoint was the rate of disease control (no progr...

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Bibliographic Details
Main Authors: Patrick Schöffski, Vincente Guillem, Margarita Garcia, Fernando Rivera, Josep Tabernero, Martin Cullell, Jose Antonio Lopez-Martin, Patricia Pollard, Herlinde Dumez, Xavier Garcia del Muro, Luis Paz-Ares
Format: Article
Language:English
Published: MDPI AG 2009-03-01
Series:Marine Drugs
Subjects:
Aplidin
L-carnitine
plitidepsin
renal cell carcinoma
vascular endothelial growth factor
Online Access:http://www.mdpi.com/1660-3397/7/1/57/

Internet

http://www.mdpi.com/1660-3397/7/1/57/

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