Spike burst-pause dynamics of Purkinje cells regulate sensorimotor adaptation.

Cerebellar Purkinje cells mediate accurate eye movement coordination. However, it remains unclear how oculomotor adaptation depends on the interplay between the characteristic Purkinje cell response patterns, namely tonic, bursting, and spike pauses. Here, a spiking cerebellar model assesses the rol...

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Bibliographic Details
Main Authors: Niceto R Luque, Francisco Naveros, Richard R Carrillo, Eduardo Ros, Angelo Arleo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006298