PAN3–PSMA2 fusion resulting from a novel t(7;13)(p14;q12) chromosome translocation in a myelodysplastic syndrome that evolved into acute myeloid leukemia

PAN3–PSMA2 fusion resulting from a novel t(7;13)(p14;q12) chromosome translocation in a myelodysplastic syndrome that evolved into acute myeloid leukemia

Abstract Background Acquired primary chromosomal changes in cancer are sometimes found as sole karyotypic abnormalities. They are specifically associated with particular types of neoplasia, essential in establishing the neoplasm, and they often lead to the generation of chimeric genes of pathogeneti...

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Bibliographic Details
Main Authors: Ioannis Panagopoulos, Ludmila Gorunova, Hege Kilen Andersen, Astrid Bergrem, Anders Dahm, Kristin Andersen, Francesca Micci, Sverre Heim
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Experimental Hematology & Oncology
Subjects:
Myelodysplastic syndrome
Acute myeloid leukemia
Chromosome translocation
t(7;13)(p14;q12)
RNA sequencing
PAN3–PSMA2 fusion
Online Access:http://link.springer.com/article/10.1186/s40164-018-0099-4

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http://link.springer.com/article/10.1186/s40164-018-0099-4

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