E2F1 Hinders Skin Wound Healing by Repressing Vascular Endothelial Growth Factor (VEGF) Expression, Neovascularization, and Macrophage Recruitment.

E2F1 Hinders Skin Wound Healing by Repressing Vascular Endothelial Growth Factor (VEGF) Expression, Neovascularization, and Macrophage Recruitment.

Refractory surface of wound and dermal chronic ulcer are largely attributed to poor neovascularization. We have previously shown that E2F1 suppresses VEGF expression in the ischemic heart, and that genetic deletion of E2F1 leads to better cardiac recovery. However, whether E2F1 has a role in dermal...

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Bibliographic Details
Main Authors: Ningning Wang, Yiping Wu, Ning Zeng, Haiping Wang, Pei Deng, Yi Xu, Youping Feng, Hong Zeng, Hongxia Yang, Kai Hou, Andrew Wang, Keshav Parthasarathy, Samaksh Goyal, Gangjian Qin, Min Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4973919?pdf=render

Internet

http://europepmc.org/articles/PMC4973919?pdf=render

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