p180 promotes the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum.
In metazoans, the majority of mRNAs coding for secreted and membrane-bound proteins are translated on the surface of the endoplasmic reticulum (ER). Although the targeting of these transcripts to the surface of the ER can be mediated by the translation of a signal sequence and their maintenance is m...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS Biology |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22679391/?tool=EBI |