PIK3CA-mediated PI3-kinase signalling is essential for HPV-induced transformation <it>in vitro</it>

<p>Abstract</p> <p>Background</p> <p>High-risk human papillomavirus (hrHPV) infections are causally related to cervical cancer development. The additional (epi)genetic alterations driving malignant transformation of hrHPV-infected cells however, are not yet fully elucid...

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Bibliographic Details
Main Authors: Broker Thomas R, Rösl Frank, De-Castro Arce Johanna, Meijer Chris JLM, Snijders Peter JF, Banerjee N Sanjib, Henken Florianne E, Chow Louise T, Steenbergen Renske DM
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/10/1/71