Downregulation of RIF1 Enhances Sensitivity to Platinum-Based Chemotherapy in Epithelial Ovarian Cancer (EOC) by Regulating Nucleotide Excision Repair (NER) Pathway

Downregulation of RIF1 Enhances Sensitivity to Platinum-Based Chemotherapy in Epithelial Ovarian Cancer (EOC) by Regulating Nucleotide Excision Repair (NER) Pathway

Background/Aims: Rap1 interacting factor 1 (RIF1) was deemed to be involved in replication timing regulation and DNA damage response. However, little is known about the role of RIF1 in malignancies. Thus, this study aimed to investigate whether the expression of RIF1 is relevant to the response of e...

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Bibliographic Details
Main Authors: Yong-Bin Liu, Ying Mei, Zheng-Wen Tian, Jing Long, Chen-Hui Luo, Hong-Hao Zhou
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Ovarian Cancer
RIF1 (Rap1 interacting factor 1)
Cisplatin
NER (nucleotide excision repair)
Drug Resistance
Online Access:https://www.karger.com/Article/FullText/489418

Internet

https://www.karger.com/Article/FullText/489418

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