Selenium supplementation to improve bone health in postmenopausal women: the SeMS three-arm RCT

Selenium supplementation to improve bone health in postmenopausal women: the SeMS three-arm RCT

Background: Observational and pre-clinical studies have reported an association between selenium status, bone density, bone turnover and fracture risk. Selenium is an anti-oxidant, so we hypothesised that selenium could reduce the pro-resorptive action of reactive oxygen species on osteoclasts. Popu...

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Bibliographic Details
Main Authors: Jennifer S Walsh, Richard Jacques, Lutz Schomburg, Tom Hill, John Mathers, Graham Williams, Richard Eastell
Format: Article
Language:English
Published: NIHR Journals Library 2021-04-01
Series:Efficacy and Mechanism Evaluation
Subjects:
selenium
osteoporosis
bone remodelling
bone density
physical function
antioxidants
Online Access:https://doi.org/10.3310/eme08060

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