Exosomal miR-27a Derived from Gastric Cancer Cells Regulates the Transformation of Fibroblasts into Cancer-Associated Fibroblasts

Exosomal miR-27a Derived from Gastric Cancer Cells Regulates the Transformation of Fibroblasts into Cancer-Associated Fibroblasts

Background/Aims: The malignant biological behavior of gastric cancer(GC) is not only determined by cancer cells alone, but also closely regulated by the microenvironment. Fibroblasts represent a large proportion of the components in the tumor microenvironment, and they promote the development of dis...

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Bibliographic Details
Main Authors: Jingya Wang, Xuwen Guan, Yue Zhang, Shaohua Ge, Le Zhang, Hongli Li, Xia Wang, Rui Liu, Tao Ning, Ting Deng, Haiyang Zhang, Xiangli Jiang, Yi Ba, Dingzhi Huang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
miR-27a
Cancer associated fibroblasts
Exosome
Gastric cancer
CSRP2
Tumor microenvironment
Online Access:https://www.karger.com/Article/FullText/493218

Internet

https://www.karger.com/Article/FullText/493218

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