Mesenchymal stem cells repress Th17 molecular program through the PD-1 pathway.

MSC display potent suppressive properties initially described a decade ago. More recently, MSC suppressive activities on T-cell effector pathways have been investigated. MSC modulate CD4 differentiation through different mechanisms depending on culture conditions and display disparate activities on...

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Bibliographic Details
Main Authors: Patricia Luz-Crawford, Danièle Noël, Ximena Fernandez, Maroun Khoury, Fernando Figueroa, Flavio Carrión, Christian Jorgensen, Farida Djouad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3444478?pdf=render