Limitations in the Design of Chimeric Antigen Receptors for Cancer Therapy

Cancer therapy has entered a new era, transitioning from unspecific chemotherapeutic agents to increasingly specific immune-based therapeutic strategies. Among these, chimeric antigen receptor (CAR) T cells have shown unparalleled therapeutic potential in treating refractory hematological malignanci...

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Bibliographic Details
Main Authors: Stefan Stoiber, Bruno L. Cadilha, Mohamed-Reda Benmebarek, Stefanie Lesch, Stefan Endres, Sebastian Kobold
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/5/472