Oncological evaluation in the perioperative period using cfDNA with BRAF V600E mutation in patients with colorectal cancer

Oncological evaluation in the perioperative period using cfDNA with BRAF V600E mutation in patients with colorectal cancer

Abstract The detection of circulating cell-free DNA (cfDNA) by liquid biopsy is reported to provide prognostic information in colorectal cancer (CRC). Although the frequency of BRAF V600E mutation in CRC is less than 10%, it is associated with poor responses to conventional chemotherapy. We conducte...

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Bibliographic Details
Main Authors: Keita Tanaka, Yoichiro Yoshida, Teppei Yamada, Takaomi Hayashi, Hideki Shimaoka, Fumihiro Yoshimura, Ryuji Kajitani, Taro Munechika, Yoshiko Matsumoto, Hideki Nagano, Akira Komono, Ryohei Sakamoto, Ryo Nakashima, Naoya Aisu, Gumpei Yoshimatsu, Suguru Hasegawa
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92795-8

Internet

https://doi.org/10.1038/s41598-021-92795-8

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