Eukaryotic Initiation Factor 4A-3: A Review of Its Physiological Role and Involvement in Oncogenesis

Eukaryotic Initiation Factor 4A-3: A Review of Its Physiological Role and Involvement in Oncogenesis

EIF4A3, a member of the DEAD-box protein family, is a nuclear matrix protein and a core component of the exon junction complex (EJC). Under physiological conditions, EIF4A3 participates in post-transcriptional gene regulation by promoting EJC control of precursor mRNA splicing, thus influencing nons...

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Bibliographic Details
Main Authors: Jiazhou Ye, Xiaomin She, Ziyu Liu, Ziqin He, Xing Gao, Lu Lu, Rong Liang, Yan Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
EIF4A3
cancer
lncRNAs
posttranscriptional regulation
cancer molecular targets and therapeutics
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.712045/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.712045/full

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