MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors.

MicroRNA (miRNA) expression profiles have been described in pancreatic ductal adenocarcinoma (PDAC), but these have not been compared with pre-malignant pancreatic tumors. We wished to compare the miRNA expression signatures in pancreatic benign cystic tumors (BCT) of low and high malignant potentia...

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Bibliographic Details
Main Authors: Long R Jiao, Adam E Frampton, Jimmy Jacob, Loredana Pellegrino, Jonathan Krell, Georgios Giamas, Nicole Tsim, Panagiotis Vlavianos, Patrizia Cohen, Raida Ahmad, Andreas Keller, Nagy A Habib, Justin Stebbing, Leandro Castellano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3284550?pdf=render