Cytotoxicity of Oleandrin Is Mediated by Calcium Influx and by Increased Manganese Uptake in <i>Saccharomyces cerevisiae</i> Cells

Oleandrin, the main component of <i>Nerium oleander</i> L. extracts, is a cardiotoxic glycoside with multiple pharmacological implications, having potential anti-tumoral and antiviral characteristics. Although it is accepted that the main mechanism of oleandrin action is the inhibition o...

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Bibliographic Details
Main Authors: Lavinia L. Ruta, Claudia V. Popa, Ileana C. Farcasanu
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/18/4259