Antigen processing by macroautophagy for MHC presentation

T cells recognize antigen fragments, presented to them by MHC molecules. It lies in the interest of the immune system to display a maximal diversity of these peptides and utilize all catabolic processes to generate them. Macroautophagy, a pathway that delivers cytoplasmic constituents for lysosomal...

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Bibliographic Details
Main Author: Christian eMunz
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-09-01
Series:Frontiers in Immunology
Subjects:
Atg
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00042/full