N-Acetylcysteine Attenuates Hyperalgesia in Rats with Diabetic Neuropathic Pain: Role of Oxidative Stress and Inflammatory Mediators and CXCR4

Objectives. CXCR4 plays critical roles in the development of diabetic neuropathic pain (DNP) in rats, and its mechanism is unknown. This study was aimed at evaluating the potential therapeutic value of the antioxidant N-acetylcysteine (NAC) against DNP in rats and how CXCR4 participates in the forma...

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Bibliographic Details
Main Authors: Sisi Li, Xuying Li, Xiangbin Xie, Xiao Wei, Cong Yu, Chi Wai Cheung, Zhengyuan Xia, Guogang Tian
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2021/8862910