Enhancement by LDL of transfer of L-4F and oxidized lipids to HDL in C57BL/6J mice and human plasma

Enhancement by LDL of transfer of L-4F and oxidized lipids to HDL in C57BL/6J mice and human plasma

The apoA-I mimetic peptide L-4F [(Ac-D-W-F-K-A-F-Y-D-K-V-A-E-K-F-K-E-A-F-NH2) synthesized from all L-amino acids] has shown potential for the treatment of a variety of diseases. Here, we demonstrate that LDL promotes association between L-4F and HDL. A 2- to 3-fold greater association of L-4F with h...

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Bibliographic Details
Main Authors: David Meriwether, Satoshi Imaizumi, Victor Grijalva, Greg Hough, Ladan Vakili, G.M. Anantharamaiah, Robin Farias-Eisner, Mohamad Navab, Alan M. Fogelman, Srinivasa T. Reddy, Ishaiahu Shechter
Format: Article
Language:English
Published: Elsevier 2011-10-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
apolipoprotein A-I
apolipoprotein A-I mimetic peptides
lipoproteins
high density lipoprotein
low density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520408442

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http://www.sciencedirect.com/science/article/pii/S0022227520408442

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