Mitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen families.
Malaria parasites elude eradication attempts both within the human host and across nations. At the individual level, parasites evade the host immune responses through antigenic variation. At the global level, parasites escape drug pressure through single nucleotide variants and gene copy amplificati...
Main Authors: | Selina E R Bopp, Micah J Manary, A Taylor Bright, Geoffrey L Johnston, Neekesh V Dharia, Fabio L Luna, Susan McCormack, David Plouffe, Case W McNamara, John R Walker, David A Fidock, Eros Lazzerini Denchi, Elizabeth A Winzeler |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3567157?pdf=render |
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