Sodium/glucose cotransporter 2 and renoprotection: From the perspective of energy regulation and water conservation

Sodium/glucose cotransporter 2 (SGLT2) is a renal low-affinity high-capacity sodium/glucose cotransporter expressed in the apical membrane of the early segment of proximal tubules. SGLT2 reabsorbs filtered glucose in the kidney, and its inhibitors represent a new class of oral medications used for t...

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Bibliographic Details
Main Authors: Kento Kitada, Satoshi Kidoguchi, Daisuke Nakano, Akira Nishiyama
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861321000736