PTEN: Tumor Suppressor and Metabolic Regulator

Phosphatase and Tensin Homolog deleted on Chromosome 10 (PTEN) is a dual phosphatase with both protein and lipid phosphatase activities. PTEN was first discovered as a tumor suppressor with growth and survival regulatory functions. In recent years, the function of PTEN as a metabolic regulator has a...

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Bibliographic Details
Main Authors: Chien-Yu Chen, Jingyu Chen, Lina He, Bangyan L. Stiles
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Endocrinology
Subjects:
AKT
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00338/full