Compensatory Mechanisms Modulate the Neuronal Excitability in a Kainic Acid-Induced Epilepsy Mouse Model

Compensatory Mechanisms Modulate the Neuronal Excitability in a Kainic Acid-Induced Epilepsy Mouse Model

Epilepsy is one of the most common neurological disorders affecting millions of people. Due to the complicated and unclear mechanisms of epilepsy, still a significant proportion of epilepsy patients remain poorly controlled. Epilepsy is characterized by convulsive seizures that are caused by increas...

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Bibliographic Details
Main Authors: Gaojie Pan, Zhicai Chen, Honghua Zheng, Yunwu Zhang, Huaxi Xu, Guojun Bu, Hui Zheng, Yanfang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Neural Circuits
Subjects:
epilepsy
kainic acid
hyperexcitability
synaptic transmission
γ-aminobutyric acid
tonic inhibition
Online Access:https://www.frontiersin.org/article/10.3389/fncir.2018.00048/full

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https://www.frontiersin.org/article/10.3389/fncir.2018.00048/full

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