Harnessing the Effect of Adoptively Transferred Tumor-Reactive T Cells on Endogenous (Host-Derived) Antitumor Immunity

Adoptive T cell transfer therapy, the ex vivo activation, expansion, and subsequent administration of tumor-reactive T cells, is already the most effective therapy against certain types of cancer. However, recent evidence in animal models and clinical trials suggests that host conditioning intervent...

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Bibliographic Details
Main Authors: Yolanda Nesbeth, Jose R. Conejo-Garcia
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2010/139304