A DNA Methylation Signature of Addiction in T Cells and Its Reversal With DHEA Intervention

A DNA Methylation Signature of Addiction in T Cells and Its Reversal With DHEA Intervention

Previous studies in animal models of cocaine craving have delineated broad changes in DNA methylation profiles in the nucleus accumbens. A crucial factor for progress in behavioral and mental health epigenetics is the discovery of epigenetic markers in peripheral tissues. Several studies in primates...

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Bibliographic Details
Main Authors: Elad Lax, Gal Warhaftig, David Ohana, Rachel Maayan, Yael Delayahu, Paola Roska, Alexander M. Ponizovsky, Abraham Weizman, Gal Yadid, Moshe Szyf
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
dehydroepiandrosterone (DHEA)
DNA methylation
drug abuse
genome-wide analysis
drug-addiction
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00322/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00322/full

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