Apoptosis induced by proteasome inhibition in human myoblast cultures

Dysfunction of the ubiquitin-proteasome system has recently been implicated in the pathogenesis of some untreatable myodegenerative diseases characterized by the formation of ubiquitinated inclusions in skeletal muscles. We have developed an in vitro model of proteasomal dysfunction by applying inhi...

Full description

Bibliographic Details
Main Authors: J Sassone, A Ciammola, C Tiloca, M Glionna, G Meola, E Mancinelli, V Silani
Format: Article
Language:English
Published: PAGEPress Publications 2009-06-01
Series:European Journal of Histochemistry
Online Access:https://www.ejh.it/index.php/ejh/article/view/981