Cycloastragenol as an Exogenous Enhancer of Chondrogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells. A Morphological Study

Cycloastragenol as an Exogenous Enhancer of Chondrogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells. A Morphological Study

Stem cell therapy and tissue engineering represent a promising approach for cartilage regeneration. However, they present limits in terms of mechanical properties and premature de-differentiation of engineered cartilage. Cycloastragenol (CAG), a triterpenoid saponin compound and a hydrolysis product...

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Bibliographic Details
Main Authors: Marta Anna Szychlinska, Giovanna Calabrese, Silvia Ravalli, Nunziatina Laura Parrinello, Stefano Forte, Paola Castrogiovanni, Elisabetta Pricoco, Rosa Imbesi, Sergio Castorina, Rosalia Leonardi, Michelino Di Rosa, Giuseppe Musumeci
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
cartilage regeneration
tissue engineering
cycloastragenol
human adipose-derived mesenchymal stem cells
chondrocyte phenotype
hypertrophy
Online Access:https://www.mdpi.com/2073-4409/9/2/347

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https://www.mdpi.com/2073-4409/9/2/347

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