Total and Regional White Matter Lesions Are Correlated With Motor and Cognitive Impairments in Carriers of the FMR1 Premutation

Total and Regional White Matter Lesions Are Correlated With Motor and Cognitive Impairments in Carriers of the FMR1 Premutation

This study explores the relationships between hemispheric and cerebellar white matter lesions and motor and cognitive impairments in male carriers of Fragile-X Mental Retardation 1 (FMR1) premutation alleles, and in a subgroup of these carriers affected with Fragile X-Associated Tremor/Ataxia syndro...

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Bibliographic Details
Main Authors: Darren R. Hocking, Danuta Z. Loesch, Nicholas Trost, Minh Q. Bui, Eleanor Hammersley, David Francis, Flora Tassone, Elsdon Storey
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Neurology
Subjects:
FMR1 premutation carriers
FXTAS
MRI
white matter hyperintensities
motor scores
cognitive impairment
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00832/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.00832/full

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