Impact of Aortic Stenosis on Myofiber Stress: Translational Application of Left Ventricle-Aortic Coupling Simulation

Impact of Aortic Stenosis on Myofiber Stress: Translational Application of Left Ventricle-Aortic Coupling Simulation

The severity of aortic stenosis (AS) has traditionally been graded by measuring hemodynamic parameters of transvalvular pressure gradient, ejection jet velocity, or estimating valve orifice area. Recent research has highlighted limitations of these criteria at effectively grading AS in presence of l...

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Bibliographic Details
Main Authors: Andrew D. Wisneski, Yunjie Wang, Tobias Deuse, Arthur C. Hill, Salvatore Pasta, Kevin L. Sack, Jiang Yao, Julius M. Guccione
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Physiology
Subjects:
aortic stenosis
finite element method
myofiber stress
ventricular function
realistic simulation
ventricle-aortic coupling
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.574211/full

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https://www.frontiersin.org/article/10.3389/fphys.2020.574211/full

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