Lithium is able to minimize olanzapine oxidative-inflammatory induction on macrophage cells.

BACKGROUND:Olanzapine (OLZ) is a second-generation antipsychotic drug used for treatment of schizophrenia, bipolar disorder, and other neuropsychiatric conditions. Undesirable side effects of OLZ include metabolic alterations associated with chronic oxidative-inflammation events. It is possible that...

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Bibliographic Details
Main Authors: Marcelo Soares Fernandes, Fernanda Barbisan, Verônica Farina Azzolin, Pedro Antônio Schmidt do Prado-Lima, Cibele Ferreira Teixeira, Ivo Emílio da Cruz Jung, Charles Elias Assmann, Rogerio Tomasi Riffel, Marta Maria Medeiros Frescura Duarte, Ednea Maia Aguiar-Ribeiro, Ivana Beatrice Mânica da Cruz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209223