Regulatory Interplay between miR-181a-5p and Estrogen Receptor Signaling Cascade in Breast Cancer

Regulatory Interplay between miR-181a-5p and Estrogen Receptor Signaling Cascade in Breast Cancer

The efficacy and side effects of endocrine therapy in breast cancer (BC) depend largely on estrogen receptor alpha (ERα) expression, the specific drug administered, and treatment scheduling. Although the benefits of endocrine therapy outweigh any adverse effects in the initial stages of BC, later- o...

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Bibliographic Details
Main Authors: Rosaria Benedetti, Chiara Papulino, Giulia Sgueglia, Ugo Chianese, Tommaso De Marchi, Francesco Iovino, Dante Rotili, Antonello Mai, Emma Niméus, Carmela Dell’ Aversana, Lucia Altucci
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
miR-181a-5p
ERα
breast cancer
hormone signaling
epigenetic SERD
endocrine therapy
Online Access:https://www.mdpi.com/2072-6694/13/3/543

Internet

https://www.mdpi.com/2072-6694/13/3/543

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