Potentiation of Antidepressant Effects of Agomelatine and Bupropion by Hesperidin in Mice
Hesperidin, a well-known flavanone glycoside mostly found in citrus fruits, showed neuroprotective and antidepressant activity. Agomelatine, a melatonergic MT1/MT2 agonist and 5-HT2C receptor antagonist, exhibits good antidepressant efficacy. Bupropion has been widely used for the treatment of depre...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2018-01-01
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| Series: | Neurology Research International |
| Online Access: | http://dx.doi.org/10.1155/2018/9828639 |