The nuclear envelope localization of DYT1 dystonia torsinA-ΔE requires the SUN1 LINC complex component
<p>Abstract</p> <p>Background</p> <p>DYT1 dystonia is an autosomal dominant neurological condition caused by a mutation that removes a single glutamic acid residue (ΔE) from the torsinA (torA) AAA+ protein. TorA appears to possess a nuclear envelope (NE) localized activ...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-05-01
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Series: | BMC Cell Biology |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1471-2121/12/24 |