The nuclear envelope localization of DYT1 dystonia torsinA-ΔE requires the SUN1 LINC complex component

The nuclear envelope localization of DYT1 dystonia torsinA-ΔE requires the SUN1 LINC complex component

<p>Abstract</p> <p>Background</p> <p>DYT1 dystonia is an autosomal dominant neurological condition caused by a mutation that removes a single glutamic acid residue (ΔE) from the torsinA (torA) AAA+ protein. TorA appears to possess a nuclear envelope (NE) localized activ...

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Bibliographic Details
Main Authors: Jeong Danielle Y, Kumar Dhivya, Jungwirth Michael T, Goodchild Rose E
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Cell Biology
Subjects:
torsinA
LINC complex
AAA+ protein
Nuclear Envelope
SUN1
DYT1 dystonia
Online Access:http://www.biomedcentral.com/1471-2121/12/24

Internet

http://www.biomedcentral.com/1471-2121/12/24

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