The two-component system CepRS regulates the cephamycin C biosynthesis in Streptomyces clavuligerus F613-1

The two-component system CepRS regulates the cephamycin C biosynthesis in Streptomyces clavuligerus F613-1

Abstract During industrial fermentation, Streptomyces clavuligerus F613-1 simultaneously produces primary product clavulanic acid (CA) and cephamycin C. The cephamycin C biosynthetic gene cluster and pathway have been basically elucidated and the CcaR positive regulator was found to control the ceph...

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Bibliographic Details
Main Authors: Jiafang Fu, Ronghuo Qin, Gongli Zong, Chuanqing Zhong, Peipei Zhang, Ni Kang, Xiaoyu Qi, Guangxiang Cao
Format: Article
Language:English
Published: SpringerOpen 2019-07-01
Series:AMB Express
Subjects:
Streptomyces clavuligerus
CepRS
Cephamycin C
Clavulanic acid
Online Access:http://link.springer.com/article/10.1186/s13568-019-0844-z

Internet

http://link.springer.com/article/10.1186/s13568-019-0844-z

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