Sera from Visceral Leishmaniasis Patients Display Oxidative Activity and Affect the TNF-α Production by Macrophages In Vitro

Mammalian protection against leishmanial infection depends on the development of an effective immune response. Zoonotic visceral leishmaniasis (ZVL) patients are usually unable to mount an effective immune response against the parasite and indeed appear to be severely immunosuppressed. This suppress...

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Bibliographic Details
Main Authors: Neci M. Soares, Joelma N. de Souza, Tatiana F. Leal, Eliana A. G. Reis, Maria S. Miranda, Washington L. C. dos Santos, Márcia C. A. Teixeira
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/5861453