Translation control of Enterovirus A71 gene expression

Abstract Upon EV-A71 infection of a host cell, EV-A71 RNA is translated into a viral polyprotein. Although EV-A71 can use the cellular translation machinery to produce viral proteins, unlike cellular translation, which is cap-dependent, the viral RNA genome of EV-A71 does not contain a 5′ cap and th...

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Bibliographic Details
Main Authors: Ming-Chih Lai, Han-Hsiang Chen, Peng Xu, Robert Y. L. Wang
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Biomedical Science
Subjects:
Online Access:https://doi.org/10.1186/s12929-019-0607-9