In vivo substrates of the lens molecular chaperones αA-crystallin and αB-crystallin.

αA-crystallin and αB-crystallin are members of the small heat shock protein family and function as molecular chaperones and major lens structural proteins. Although numerous studies have examined their chaperone-like activities in vitro, little is known about the proteins they protect in vivo. To el...

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Bibliographic Details
Main Authors: Usha P Andley, James P Malone, R Reid Townsend
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3997384?pdf=render