Complete regression of cutaneous metastases with systemic immune response in a patient with triple negative breast cancer receiving p53MVA vaccine with pembrolizumab

Complete regression of cutaneous metastases with systemic immune response in a patient with triple negative breast cancer receiving p53MVA vaccine with pembrolizumab

A heavily pretreated patient with triple negative breast cancer distinguished by cutaneous metastases received p53MVA vaccine in combination with pembrolizumab. Her cutaneous metastases regressed and after 2 cycles of therapy, a skin biopsy showed a complete pathological response. Systemic response...

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Bibliographic Details
Main Authors: Yuan Yuan, Ferdynand J. Kos, Ting-Fang He, Hongwei H. Yin, Mengsha Li, Nicola Hardwick, Kathryn Zurcher, Daniel Schmolze, Peter Lee, Raju K. Pillai, Vincent Chung, Don J. Diamond
Format: Article
Language:English
Published: Taylor & Francis Group 2017-12-01
Series:OncoImmunology
Subjects:
immunotherapy
mva
p53
pd-1
pembrolizumab
triple negative breast cancer
t cell response
vaccine
vaccinia
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1363138

Internet

http://dx.doi.org/10.1080/2162402X.2017.1363138

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