The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling

The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling

Interaction between the nascent polypeptide chain and the ribosomal exit tunnel can modulate the rate of translation and induce translational arrest to regulate expression of downstream genes. The ribosomal tunnel also provides a protected environment for initial protein folding events. Here, we pre...

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Bibliographic Details
Main Authors: Ting Su, Jingdong Cheng, Daniel Sohmen, Rickard Hedman, Otto Berninghausen, Gunnar von Heijne, Daniel N Wilson, Roland Beckmann
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-05-01
Series:eLife
Subjects:
stalling
ribosome
cryo-EM
VemP
protein folding
Vibrio alginolyticus
Online Access:https://elifesciences.org/articles/25642

Internet

https://elifesciences.org/articles/25642

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