Suppression of Type I Interferon Signaling by <i>Flavivirus</i> NS5

Type I interferon (IFN-I) is the first line of mammalian host defense against viral infection. To counteract this, the flaviviruses, like other viruses, have encoded a variety of antagonists, and use a multi-layered molecular defense strategy to establish their infections. Among the most potent anta...

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Bibliographic Details
Main Authors: Stephanie Thurmond, Boxiao Wang, Jikui Song, Rong Hai
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Viruses
Subjects:
NS5
Online Access:https://www.mdpi.com/1999-4915/10/12/712