Reactive oxygen species and p47phox activation are essential for the <it>Mycobacterium tuberculosis</it>-induced pro-inflammatory response in murine microglia

<p>Abstract</p> <p>Background</p> <p>Activated microglia elicits a robust amount of pro-inflammatory cytokines, which are implicated in the pathogenesis of tuberculosis in the central nervous system (CNS). However, little is known about the intracellular signaling mecha...

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Bibliographic Details
Main Authors: Lee Dong-Seok, Lee Young-Ho, Shin Dong-Min, Lee Sung Joong, Kim Jeong-Ah, Lee Ji-Yeon, Lee Hye-Mi, Yang Chul-Su, El-Benna Jamel, Jo Eun-Kyeong
Format: Article
Language:English
Published: BMC 2007-11-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/4/1/27