Altered Expression of Wnt Signaling Pathway Components in Osteogenesis of Mesenchymal Stem Cells in Osteoarthritis Patients.

Altered Expression of Wnt Signaling Pathway Components in Osteogenesis of Mesenchymal Stem Cells in Osteoarthritis Patients.

INTRODUCTION:Osteoarthritis (OA) is characterized by altered homeostasis of joint cartilage and bone, whose functional properties rely on chondrocytes and osteoblasts, belonging to mesenchymal stem cells (MSCs). WNT signaling acts as a hub integrating and crosstalking with other signaling pathways l...

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Main Authors: Pilar Tornero-Esteban, Ascensión Peralta-Sastre, Eva Herranz, Luis Rodríguez-Rodríguez, Arkaitz Mucientes, Lydia Abásolo, Fernando Marco, Benjamín Fernández-Gutiérrez, José Ramón Lamas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4564164?pdf=render

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http://europepmc.org/articles/PMC4564164?pdf=render

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