Matrix metalloprotease polymorphisms are associated with gas transfer in alpha 1 antitrypsin deficiency

Alpha-1-antitrypsin deficiency (AATD) is associated with variable development of emphysema and other features of chronic obstructive pulmonary disease (COPD). Matrix metalloproteinases (MMPs) are believed to be important in the pathophysiology of COPD, and may therefore confer susceptibility to this...

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Bibliographic Details
Main Authors: Christopher J. McAloon, Alice M. Wood, Stephen C. Gough, Robert A. Stockley
Format: Article
Language:English
Published: SAGE Publishing 2009-02-01
Series:Therapeutic Advances in Respiratory Disease
Online Access:https://doi.org/10.1177/1753465809102263